Mohamed was born in Mansoura (North of Egypt) in 1953 where he spent his childhood and graduated from school. In 1973, Mohamed moved to Alexandria to start a five-year art study at the Faculty of Fine Arts. After graduating, he moved to Cairo where he held his first solo exhibition at the Spanish Cultural Center. In 1978 Mohamed started a seven-year journey to Europe, where he visited museums in Spain, France, Belgium and Germany and held his first international solo exhibition at the Hohmann Gallery in Northern Germany. Two years after his first international solo exhibition, Mohamed moved to Vienna to study graphics and to exhibit at the AAI Gallery. Later he moved to Zurich where he studied graphic and sculpture and had a two-year experience in Art Therapy.
Mohamed has held many solo and group exhibitions in Egypt at Cairo Atelier, Mashrabeya Gallery, Sheba Gallery, Berlin Art Gallery as well as Zamalek Art Gallery and participated in several group exhibitions in the Kunst Museum Bonn. Alongside his list of both solo and group exhibitions, Mohamed also participated in several international events including Havana Biennale.
He founded The Fayoum Art Center where artists get to meet, work and collaborate in 2007 and established the first Caricature Museum in the Middle East in 2009. Mohamed was given various awards including the 1st Prize in Kuwait Biennale (1994) and the Grand Prix at Alexandria Biennale (1997). The artist currently lives in Egypt and works between Cairo, Fayoum and Germany.